Research and Administrative Assistant

2021-10-14
Beverly, MA, USA
Adept Therapeutics Inc.
We are seeking highly organized, collaborative and self-motivated Assistant to join us discovering and developing antibody therapeutics to modulate novel and challenging therapeutic targets in Immuno-Oncology. The successful candidate will assist in performing preclinical research experiments, as well as laboratory and administrative operations, including but not limited to financial and personnel resources for the CEO and the company, to ensure the efficient and effective day-to-day management of the activities. The successful candidate should be flexible, ready to troubleshoot, and have excellent communication and teamwork skill to ensure smooth co-ordination and completion of assigned tasks and activities. Full training will be provided. We sponsor H-1 visa application and offer global business travel and working opportunity. If interested, please send your resume to ------------JOB-SPECIFIC RESPONSIBILITIES Perform molecular and cellular experiments, including but not limited to PCR, electrophoresis, plasmid construction, western blot, protein engineering, protein expression and purification, cell culture of cell lines, transient and stable transfection, isolation, phenotyping and culture of human, monkey and/or rodent primary cells.Learn and apply company platform technology, including but not limited to hybridoma generation, high-throughput single B cell cloning/culture, 96-well transfection, production /purification and quantification of antibodies/biologics; commitment to simultaneously handle 4-8 96-well and/or 24-well plates is required. QC of purified proteins using standard techniques, such as SDS-PAGE and SEC-HPLC.Characterization of antibodies (transfection supernatant or purified) by employing flow cytometry, ELISA, ADCC, CDC, ADCP, and/or other biochemical or cell-based assay(s).Timely document and maintain detailed experimental laboratory notebooks; generate and analyze appropriately high-quality experimental results for the preparation presentation for internal/external use. Draft and/or review technical reports/research protocols/SOPs, and scientific manuscript for patent application and/or publication.Support external collaborations, including CROs and academic laboratories. Work with the CEO, CSO, consultants and researchers on developing and updating company polices, operational and administrative procedures, and laboratory research protocols; coordinate their reviews and approvals; coordinate and ensure all lab activities comply with regulatory requirement.Provide day-to-day management of lab resources to optimize supply inventory and ensure adequate resources for multiple projects; coordinate purchases and maintenance of lab equipment; process financial transactions and ordersAct as the companys point of contact for government agencies, external partners and vendors, including but not limited to EHS, Business Operations, Research Compliance, HR.Coordinate visits of clients, collaborators and investorsWork at a fast pace and adapt to changing priorities to meet program and team needs.Such other responsibilities for research and administrative assistant as may be assigned from time to time, QUALIFICATIONS B.S. in molecular biology, cell biology, immunology, biochemistry, biomedical engineering with 2+ years of working experience, preferably in a lab environment.Extensive hands-on experience in molecular biology and/or basic cell culture skills, including PCR, DNA and protein electrophoresis, molecular cloning, primary and/or cell line culture.Experience of transient/stable transfection, cell line generation, or cell-based assay is a plus. Experience with lab and administrative is a plus.Track record of demonstrating analytical skills, bench skills and problem-solving skills.Must be a team player and collaborator in a fast-growing environment.Excellent verbal and written communication and interpersonal skills, planning / organization and attention to detail. Demonstrated ability to work independently with some supervision.BENEFITSBonus PayEmployee Incentive Plan: Stock OptionHealth Insurance BenefitRetirement Plan: 401(K) or Roth 401(K), 401(K) MatchingPaid Time Off: Holidays, Vacation days, Sick days, Personal daysFlexible Work ScheduleCOMPANY BACKGORUNDAdept Therapeutics Inc. (AdeptTx) is an innovative start-up biotech company located at Woburn and Beverly in Great Boston area, MA, with passion for following the science and committing to find potentially life-changing medicines for people with unmet medical needs. Focusing on T cells, Natural Killer (NK)cells and immune-suppressive myeloid cells, we leverage multiple advanced antibody technologies to discover fully human or humanized antibody therapeutics to enhance anti-tumor immunity. We are establishing and optimizing two unique platforms including immune cell engager bispecific antibodies and multi-functional tri-specific antibodies, which change tumor microenvironment (TME) to boost immune responses against cancer cells through 1) recruiting and activating effector immune cells and 2) modulating immune-suppressive TME to support tumor killing effector cell function. Our expertise in GPCR antibody discovery and development enables us to reach for the high-hanging fruits, the most challenging targets for therapeutic antibody discovery. Our broad product portfolio focuses on both hematological malignancies, such as cutaneous lymphomaand solid tumors including triple negative breast cancer, ovarian, colon, kidney, renal and pancreatic cancers etc.Adept Therapeutics, Inc. is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, national origin, marital, domestic partnership or civil union status, age, disability, genetic information, status as a veteran or as a member of the military or status in any group protected by applicable federal or state laws.

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